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Medchemexpress LLC Acetyl tributyl citrate (Tributyl O-acetylcitrate) | 77-90-7 | MFCD00038481 | 98.9% | 402.48 | 200 MG
Supplier: Medchemexpress LLC HYW010981200MG
Acetyl tributyl citrate (Tributyl O-acetylcitrate) is a pharmaceutical excipient and biodegradable hydrophobic plasticizer. It can be used in cosmetics, food packaging, and as a flavoring substance for food.
- Metabolizes rapidly in rat plasma with mean half-lives of 0.23 h (1 μM) and 0.21 h (10 μM).
- Rapidly metabolized in rat liver microsomes, with average half-lives of 0.27 h (1 μM) and 0.64 h (10 μM).
- Undergoes rapid metabolism in human liver microsomes, with average half-lives of 0.26 h (1 μM) and 0.37 h (10 μM).
- Metabolized by multiple human CYP isoforms, with CYP2C19 and CYP3A4 being particularly prominent at 10 μM.
- Exhibits rapid absorption and elimination in healthy male Sprague-Dawley rats, with an oral bioavailability of 27.4%.
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