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Cayman Chemical AcetylharpagIde 50mg

Supplier: Cayman Chemical 3993050 MG

An inhibitor of c-Src kinase (IC50 0.01 UM) inhibits phosphorylation of c-Src kinase Lck and c-Yes and VEGFR2 (IC50s 0.01 0.03 0.08 and 0.7 UM respectively) inhibits proliferation of NIH3T3 fibroblasts as well as PC3 DU145 and A549 cancer cells (IC50s 0.5 32 16 and 17 UM respectively) reduces tumor cell proliferation and microvessel density and increases apoptosis in an L3.6pl pancreatic cancer mouse xenograft model at 50 mg/kg per day inhibits tumor growth and metastasis in the same model in combination with gemcitabine
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