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Medchemexpress LLC Achra(97-116) | 663154-30-1 | 99.4% | 2252.56 | 1 MG
Supplier: Medchemexpress LLC HYP57661MG
AChRα(97-116) is a synthetic peptide corresponding to the 97-116 region of the rat acetylcholine receptor α-subunit, and also an inducer of autoimmune diseases. It can be used in studies related to experimental autoimmune myasthenia gravis.
- Does not induce significant proliferation of lymphocytes.
- Maintains antigen-specific immune cell phenotype responsive to dopaminergic modulation.
- Effectively detects elevated antibody levels in serum.
- Stimulates T cells to differentiate into Tfh cells.
- Stimulates lymph node-derived mononuclear cells to produce elevated percentages of pre-Tfh cells.
- Induces experimental autoimmune myasthenia gravis in Lewis rats.
- Drives elevated antibody production, reduced muscle clusters, and expansion of Tfh cells.
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