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Medchemexpress LLC Acid-PEG3-C2-Boc | 1807539-06-5 | ≥97.0% | 5 G

Supplier: Medchemexpress LLC HY1305495G
Acid-PEG3-C2-Boc is a PEG- and Alkyl/ether-based PROTAC linker. It can be utilized in the synthesis of PROTACs for the degradation of EGFR and the inhibition of mTOR. PROTACs are composed of two distinct ligands connected by a linker; one ligand is for an E3 ubiquitin ligase, and the other is for the target protein. PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG- and Alkyl/ether-based PROTAC linker
- Used in the synthesis of PROTACs
- Degrades EGFR
- Inhibits mTOR
- Leverages the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
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