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Medchemexpress LLC Acoramidis hydrochloride | 2242751-53-5 | 98.5% | 328.77 | 25 MG
Supplier: Medchemexpress LLC 25MGHY109165A
Acoramidis hydrochloride is an orally active and selective kinetic stabilizer of WT and V122I-TTR (transthyretin). It is used in the study for transthyretin amyloidosis.
- Solid appearance
- Color white to light yellow
- Soluble in DMSO (62.5 mg/mL), insoluble in H2O
- Stabilizes V122I- and WT-TTR
- Stimulates mitochondrial QO2
- Shows minimal inhibition of hERG and cytochrome P450 isozymes
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