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Medchemexpress LLC Acp-5862 | 2230757-47-6 | 98.3% | 481.51 g/mol | C26H23N7O3 | 5 MG
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Supplier:  Medchemexpress LLC HY1353345MG

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ACP-5862 is the major active, circulating metabolite of acalabrutinib. It is a pyrrolidine ring-opened small molecule that potently inhibits Bruton tyrosine kinase (BTK) with an IC50 of 5.0 nM and displays weak time-dependent inactivation of CYP3A4 and CYP2C8.

  • Potent BTK inhibition with reported IC50 of 5.0 nM.
  • Useful for metabolite profiling and pharmacology studies.
  • High reported purity (≈98.3%) suitable for research use.
  • Available in small milligram package sizes for discovery work.
  • Storage-stable under recommended powder and solvent conditions.
  • Well characterized: molecular weight 481.51 and formula C26H23N7O3.

Catalog No. 50-002-22983


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