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Cayman Chemical AcrIdIn Ornge 10-nonylbro 10mg
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Supplier:  Cayman Chemical 2554510 MG

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A selective ETA receptor antagonist (IC50s 21 and 10000 nM for human recombinant ETA and ETB respectively) inhibits ET-1-induced growth of HEY OVCA 433 SKOV3 and A2780 cells in vitro reduces ET-1-induced expression of MMP-2 MMP-9 VEGF COX-1 and COX-2 in HEY cells reduces tumor growth in an HEY mouse xenograft model in a dose-dependent manner (10-50 mg/kg per day)

Catalog No. 50-301-5933


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