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Medchemexpress LLC ACT-1004-1239 | 2178049-58-4 | 98.8% | C27H28F2N6O3 | 1 ML
SDP

Supplier:  Medchemexpress LLC HY14261710MM/1ML

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ACT-1004-1239 is a potent, selective, orally active CXCR7 antagonist with an IC50 value of 3.2 nM. It is intended for research use only and not sold to patients.

  • Inhibits human, dog, rat, mouse, guinea pig, and macaque CXCR7 with IC50s ranging from 0.6 to 3.2 nM.
  • Promotes oligodendrocyte precursor cell (OPC) differentiation by increasing CXCL12 levels.
  • Increases plasma CXCL12 concentration in vivo.
  • Reduces disease severity in an EAE model.
  • Increases myelination in a Cuprizone-induced demyelination model.

Catalog No. 50-003-53571


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