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Medchemexpress LLC ACT-1004-1239 | 2178049-58-4 | 98.8% | C27H28F2N6O3 | 50 MG
SDP

Supplier:  Medchemexpress LLC HY14261750MG

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ACT-1004-1239 is a potent, selective, and orally active CXCR7 antagonist with an IC50 value of 3.2 nM. It promotes oligodendrocyte precursor cell (OPC) differentiation by increasing CXCL12 levels. In animal models, it has been shown to reduce disease severity in myelin oligodendrocyte glycoprotein (MOG)-induced experimental autoimmune encephalomyelitis (EAE) and increase myelination in Cuprizone-induced demyelination models. This product is for research use only.

  • Potent, selective, and orally active CXCR7 antagonist
  • IC50 value of 3.2 nM
  • Promotes oligodendrocyte precursor cell (OPC) differentiation
  • Increases CXCL12 levels
  • Reduces disease severity in MOG-induced experimental autoimmune encephalomyelitis (EAE) in animal models
  • Increases myelination in Cuprizone-induced demyelination models
  • For research use only

Catalog No. 50-003-55588


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