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Medchemexpress LLC ACT-660602 | 1646267-59-5 | C20H20F6N8OS | 1 ML
SDP

Catalog No. 5000375783
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ACT-660602 is an orally active antagonist of chemokine receptor (CXCR3) with an IC50 value of 204 nM. It inhibits T-cell migration and shows efficacy in an acute lung injury model, making it suitable for autoimmune disease research.

  • Inhibits T-cell migration
  • Shows efficacy in an acute lung injury model
  • Selective for CXCR3 over hERG (IC50 of 18 μM for hERG)
  • Enhances metabolic stability
  • Displays non-competitive binding mode to CXCL10 and CXCL11
  • Exhibits anti-inflammatory activity

Catalog No. 50-003-75783 Supplier Medchemexpress LLC Supplier No. HY15109610MM/1ML
May include imposed supplier surcharges.
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ACT-660602 is an orally active antagonist of chemokine receptor (CXCR3) with an IC50 value of 204 nM. It inhibits T-cell migration and shows efficacy in an acute lung injury model, making it suitable for autoimmune disease research.

  • Inhibits T-cell migration
  • Shows efficacy in an acute lung injury model
  • Selective for CXCR3 over hERG (IC50 of 18 μM for hERG)
  • Enhances metabolic stability
  • Displays non-competitive binding mode to CXCL10 and CXCL11
  • Exhibits anti-inflammatory activity

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