Actinomycin D is a polypeptide antibiotic first described by Waksman. It is bacteriostatic in nature, especially towards gram negative bacteria. Actinomycin D was the first antibiotic shown to have anti-cancer activity. Produced by several Streptomyces spp. Actinomycin is a clear, yellow liquid administered intravenously and most commonly used in the treatment of a variety of cancers. Actinomycin D can induce apoptosis in several cell lines such as lung and prostate cancer lines, and human blood lymphocytes.Used as a radiosensitizer in adjunct to radiotherapies since it can increase the radiosensitivity of tumor cells. In cell biology, actinomycin D is shown to have the ability to inhibit transcription.CAS Number: 50-76-0Molecular Weight: 1255.42 DaChemical Formula: C62H86N12O16Solubility: Clear orange solution at 50 mg/mL DMSO or 10 mg/mL MeOHStorage Temperature: +4CResearch or further manufacturing use only, not for food or drug use.