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Medchemexpress LLC Actinonin | 13434-13-4 | 98.4% | 385.50 | 50 MG
Supplier: Medchemexpress LLC HY11395250MG
Actinonin is a naturally occurring antibacterial agent produced by Actinomyces. It inhibits aminopeptidase M, aminopeptidase N, and leucine aminopeptidase, and is a potent reversible peptide deformylase (PDF) inhibitor (Ki: 0.28 nM). It also inhibits MMP-1, MMP-3, MMP-8, MMP-9, and hmeprin α, acting as an apoptosis inducer with antiproliferative and antitumor activities.
- Naturally occurring antibacterial agent.
- Inhibits aminopeptidases (M, N, leucine).
- Potent reversible peptide deformylase (PDF) inhibitor.
- Inhibits MMP-1, MMP-3, MMP-8, MMP-9, and hmeprin α.
- Induces apoptosis.
- Exhibits antiproliferative and antitumor activities.
- Active against various gram-positive and gram-negative bacteria.
- Solid appearance, white to off-white color.
- Significant antitumor activity in prostate tumor xenograft model.
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