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Enzo Life Sciences Actinonin (5mg). CAS: 13434-13-4
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Supplier:  Enzo Life Sciences ALX260128M005

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Protease inhibitor. Antibiotic. Inhibitor of aminopeptidase M, N and leucine and alanyl aminopeptidase and peptide deformylase (PDF). Inhibits MMP-1 (Ki=300nM), MMP-2 (IC50~90nM at MMP-2=5nM), MMP-3 (Ki=1’700nM), MMP-7 (IC50~3’500nM at MMP-7=19nM), MMP-8 (Ki=160nM), MMP-9 (Ki=330nM), MMP-10 (IC50~500nM at MMP-10=22nM), MMP-12 (IC50~350nM at MMP-12=4nM), and MMP-13 (IC50~100nM  at MMP-13=13nM), but not MMP-14 (IC50>1mM at MMP-14=13.6nM). Shows antitumor activity in vitro and in vivo. Apoptosis inducer. Alternative name: 3[[1-[[2-(Hydroxymethyl)-1-pyrrolidinyl]-carbonyl]-2-methylpropyl]-carbamoyl]-octanohydroxamic acid. Formula: C19H35N3O5. MW: 385.5. Purity: ≥98% (HPLC). Solubility: Soluble in 100% ethanol (20mg/ml) or DMSO (>20mg/ml). Long Term Storage: -20°C.

Catalog No. 50-200-8334


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