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AdipoGen Activin Rec IIB pAb IG-510
Supplier: AdipoGen AG25T0114C050
Polyclonal Antibody. Recognizes the extracellular domain of human and mouse ACTR-IIB. Does not cross-react with related human proteins ActR-IIecd, BMPR-IIecd, BMPR-IAecd, BMPR-IBecd or ActR-Iecd. Source Rabbit. Applications ELISA, WB. Liquid. In PBS with 1 mg/ml BSA and 0.02% sodium azide. Activin Receptor IIB ACTR-IIB is a transmembrane receptor that forms an activin receptor complex with activin type-1 receptors ACVR1, ACVR1B or ACVR1c. ACTR-IIB transduces the activin signal from the cell surface to the cytoplasm and regulates therefore many physiological and pathological processes including neuronal differentiation and neuronal survival, hair follicle development and cycling, FSH production by the pituitary gland, wound healing, extracellular matrix production, immunosuppression and carcinogenesis. Activin is also thought to have a paracrine or autocrine role in follicular development in the ovary.
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