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Cayman Chemical ACU 4429hydrochlorIde 10mg
Supplier: Cayman Chemical 3324210 MG
An RPE65 inhibitor (IC50 = 4.4 nM); reduces rod photoreceptor recovery in dark-adapted mice after photobleaching (ED50 = 0.21mg/kg); reversibly decreases the regeneration of 11-cis retinal oxime in dark-adapted mice after photobleaching (ED50 = 0.18 mg/kg); reduces lipofuscin autofluorescence and decreases RPE A2E levels in an Abca4-/-- mouse model of Stargardt disease (ED50 = 0.47 mg/kg)
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