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Medchemexpress LLC Acyclovir-d4 (Aciclovir-d4) | 1185179-33-2 | 98.7% | 229.23 | 5 MG
Supplier: Medchemexpress LLC HY17422S15MG
Acyclovir-d4 is the deuterium labeled Acyclovir. Acyclovir (Aciclovir) is a guanosine analogue and an orally active antiviral agent. It inhibits HSV-1 (IC50 of 0.85 μM), HSV-2 (IC50 of 0.86 μM) and varicella-zoster virus. Acyclovir can be phosphorylated by viral thymidine kinase (TK), and Acyclovir triphosphate interferes with viral DNA polymerization through competitive inhibition with guanosine triphosphate and obligatory chain termination. Acyclovir also prevents bacterial infections during induction therapy for acute leukaemia.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
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