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Medchemexpress LLC Adagrasib | 2326521-71-3 | >99.9% | 200 MG
Supplier: Medchemexpress LLC HY130149200MG
Adagrasib (MRTX849) is a potent, orally-available, and mutation-selective covalent inhibitor of KRAS G12C with potential antineoplastic activity. It covalently binds to KRAS G12C at the cysteine at residue 12, locking the protein in its inactive GDP-bound conformation and inhibiting KRAS-dependent signal transduction.
- Potent and orally-available.
- Mutation-selective covalent inhibitor of KRAS G12C.
- Potential antineoplastic activity.
- Inhibits KRAS-dependent signal transduction.
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