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Enzo Life Sciences ADAM17 fluorometric drug discovery kit (1x96wells)
Supplier: Enzo Life Sciences BMLAK3100001
The ADAM17 Fluorometric (also known as fluorimetric) Drug Discovery Kit is a complete assay system designed to screen ADAM17 (TACE) inhibitors using a quenched fluorogenic peptide: Mca-PLAQAV-Dpa-RSSSR-NH2. Mca fluorescence is quenched by the Dpa group until cleavage by proteases separates the two moieties. The assays are performed in a convenient 96-well microplate format. The kit is useful to screen inhibitors of ADAM17, a potential therapeutic target. The compound GM6001 is also included as a prototypic control inhibitor. Alternative name: TACE, A disintegrin and metalloproteinase 17. Applications: Fluorescent detection, HTS Activity assay.
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