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Medchemexpress LLC Adelmidrol | 1675-66-7 | 98.0% | 250 MG
Supplier: Medchemexpress LLC 250MGHYB1026
Adelmidrol exerts important anti-inflammatory effects that are partly dependent on PPARγ. It reduces NF-κB translocation and COX-2 expression.
- Palmitoylethanolamide analogue.
- Reduces NF-κB translocation, COX-2, and p-ERK expression.
- Reduces proinflammatory cytokine release.
- Reduces the incidence of nitrotyrosine and poly(ADP)ribose in the colon.
- Reduces the degree and severity of macroscopic and histologic signs of colon injury in vivo.
- Significantly reduces body weight loss in an inflammatory bowel disease model.
- Significantly reduces polymorphonuclear cell infiltration in inflamed colon.
- Potential pharmacological treatment for inflammatory bowel disease.
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