Cayman Chemical AdenosIn 5-dIphosphate 1g

Supplier:  Cayman Chemical 167781 G

19(R)-Hydroxylated prostaglandins occur in Ug/ml concentrations in the semen of certain mammalian species especially primates. In the case of humans the compounds are primarily of the PGE series and the hydroxyl stereochemistry is 15(S)19(R).{7578} 19(R)-Hydroxylated prostaglandins are also found in the seminal plasma of marsupials where F-type compounds of the 1 and 2-series predominate.{2390} The 15(R)-hydroxy epimer of these 19-hydroxylated prostaglandins is the inverse or “unnatural” isomer at C-15. The biological role of 19(R)-hydroxylated prostaglandins is not well established. In the F-series 19(R)-hydroxylation is associated with a significant loss of receptor-mediated biological activity in some assays.{1441}

Catalog No. 50-296-5449