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Medchemexpress LLC Adenosine, 8-bromo-, cyclic 3',5'-[hydrogen P(S)]-phosphorothioate], sodium salt (1:1) | 1573115-90-8 | 99.9% | 446.15 | 500 UG
SDP

Supplier:  Medchemexpress LLC HY137640A500UG

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Sp-8-Br-cAMPS sodium is a cAMP analog that activates protein kinase A (PKA). It is known to inhibit T-cell proliferation and the haemocyte non-self response in Lepidoptera larvae. This compound also inhibits phagocytosis of certain bacteria and modulates cytokine expression.

  • Activates protein kinase A (PKA) with an EC50 of 360 nM
  • Inhibits T-cell proliferation
  • Inhibits haemocyte non-self response in Lepidoptera larvae
  • Inhibits phagocytosis of *X. nematophila* and *B. subtilis*
  • Modulates cytokine expression (IFN-γ, TNF-α, IL-2, IL-4)

Catalog No. 50-003-51045


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