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Medchemexpress LLC Adenosine monophosphate | 61-19-8 | 99.8% | C10H14N5O7P | 1 ML

Supplier: Medchemexpress LLC HYA018110MM/1ML
Adenosine monophosphate (AMP) is an adenosine A1 receptor agonist and a key cellular metabolite involved in regulating energy homeostasis and signal transduction. It demonstrates significant antiviral activity against HSV-1 and HSV-2.
- Acts as an adenosine A1 receptor agonist
- Demonstrates significant antiviral activity against HSV-1 and HSV-2
- Functions as a key cellular metabolite regulating energy homeostasis and signal transduction
- Shows negligible cell toxicity at 25 to 400 μM in RAW264.7 cells
- Significantly attenuates mRNA expression of TNF-α and IL-6 in RAW264.7 cells
- Reduces recruitment of NF-κB p65 to TNF-α, IL-6, and IL-1β gene promoters
- Increases hepatic adenosine levels in C57BL/6J mice
- Improves survival rate and lowers serum AST and ALT levels in treated mice
- Attenuates necrosis and reduces infiltration of inflammatory cells in vivo
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