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Medchemexpress LLC Adiphenine hydrochloride | 50-42-0 | MFCD00008899 | 99.1% | 1 ML

Supplier: Medchemexpress LLC HYB0379A10MM/1ML
Adiphenine hydrochloride is a non-competitive inhibitor of nicotinic acetylcholine receptor (nAChR), exhibiting specific IC50s for various receptor subtypes. This compound has also demonstrated anticonvulsant effects in studies.
- Non-competitive inhibitor of nicotinic acetylcholine receptor (nAChR)
- Exhibits anticonvulsant effects
- Blocks function of α1*-nAChR, α3α4*-nAChR, α4β2- and α4β4-nAChR in various cell lines
- Decreases frequency of ACh-induced single-channel currents
- Prevents hindleg tonic-extensor component of maximal electroshock seizures in mice
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