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Eurofins Discoverx Ready-to-Assay α2A Adrenergic Receptor Frozen Cells, 2 Vials of Cells. (HTS096RTA)

Supplier:  Eurofins Discoverx HTS096RTA

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The Ready-to-Assay α2A Adrenergic Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. epinephrine and norepinephrine) based activation of ADRA2A GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses ADRA2A alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of ADRA2A, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.

Catalog No. 50-200-5870


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