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Bachem Adrenomedullin (13-52) (human)

Supplier: Bachem 4034489.0500

Adrenomedullin (13-52) (human) , H-Ser-Phe-Gly-Cys-Arg-Phe-Gly-Thr-Cys-Thr-Val-Gln-Lys-Leu-Ala-His-Gln-Ile-Tyr-Gln-Phe-Thr-Asp-Lys-Asp-Lys-Asp-Asn-Val-Ala-Pro-Arg-Ser-Lys-Ile-Ser-Pro-Gln-Gly-Tyr-NH2, 154765-05-6, C200H308N58O59S2, Mr 4533.13, 0.5mg. This adrenomedullin fragment possessed vasodilatory activity. It has been suggested to modulate receptor-mediated, but not voltage-dependent, pulmonary vascular contraction by influencing Ca2+ influx. Therefore, it has been proposed that hADM (13-52) acts as an endothelium-dependent vasodilator agent in the pulmonary vascular bed of the rat. Furthermore, this compound may act as a modulator of the vascular phases of inflammation.
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