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Medchemexpress LLC Adropin (34-76) (human, mouse, rat) | 1802086-30-1 | 98.2% | 4499.82 | 1 MG
Supplier: Medchemexpress LLC HYP48601MG
Adropin (34-76) is a secretory domain of Adropin. It can inhibit cAMP levels and glucose production in hepatocytes, exhibiting a hypoglycemic effect. This peptide also plays an antifibrotic role by inhibiting the GLI1 signaling pathway.
- Inhibits glucose production in primary cultured mouse hepatocytes.
- Decreases cAMP levels in HepG2 hepatocytes.
- Inhibits TGF-β-induced cell activation, collagen production, and fibrotic remodeling in fibroblasts.
- Plays an anti-fibrotic role by inhibiting the GLI1 signaling pathway.
- Has a hypoglycemic effect in a diet-induced obesity model of mice.
- Shows improved effect in mouse models of fibrosis.
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