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Medchemexpress LLC ADWX 1 TFA | 98.4% | 4071.85 | 1 MG
Supplier: Medchemexpress LLC HYP1409A1MG
ADWX 1 TFA is a novel peptide inhibitor that is potent and selective for Kv1.3 with an IC50 value of 1.89 pM. It inhibits Kv1.3 channel activity to specifically suppress both initial calcium signaling and NF-κB activation. This compound has demonstrated the ability to ameliorate experimental autoimmune encephalomyelitis (EAE) in rat models and is useful for studying T cell-mediated autoimmune diseases.
- Potent and selective Kv1.3 inhibitor with an IC50 of 1.89 pM
- Inhibits Kv1.3 channel activity
- Suppresses initial calcium signaling and NF-κB activation
- Ameliorates experimental autoimmune encephalomyelitis (EAE) in rat models
- Useful for studying T cell-mediated autoimmune diseases
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