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Medchemexpress LLC Aeol-10150 pentachloride | 286475-30-7 | 98.0% | 1033.24 | 5 MG
Supplier: Medchemexpress LLC HY194165MG
AEOL-10150 pentachloride is a metalloporphyrin-catalyzed antioxidant and a superoxide dismutase mimetic. It scavenges reactive oxygen species (ROS) and reactive nitrogen species (RNS), and modulates the NF-κB signaling pathway.
- Potent antioxidant and anti-inflammatory activities.
- Mitigates tissue damage caused by radiation and chemical agents like CEES.
- Synergizes with radiotherapy for anticancer effects on prostate tumors.
- Reverses CEES-induced cell viability decline, DNA damage, and reduces ROS generation.
- Attenuates skin thickening, microvesication, and DNA oxidation in CEES-induced skin injury.
- Reduces pulmonary fibrosis, collagen deposition, and inflammation in radiation-induced lung injury.
- Improves lung injury in rats with CEES inhalation injury.
- Combined with radiotherapy, it inhibits tumor growth more significantly than radiotherapy alone.
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