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Medchemexpress LLC AF-353 (Ro-4) | 865305-30-2 | 99.4% | C14H17IN4O2 | 1 ML
Supplier: Medchemexpress LLC HY1448310MM/1ML
AF-353 (Ro-4) is a potent, selective, and orally bioavailable P2X3/P2X2/3 receptor antagonist. It inhibits α,β-meATP-evoked intracellular calcium flux and reduces the purinergic response in both normal and spinal cord-injured rats.
- Potent and selective P2X3/P2X2/3 receptor antagonist
- Orally bioavailable
- Inhibits intracellular calcium flux
- Reduces purinergic response in normal and SCI rats
- Does not compromise oxygen levels or cardiac function
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