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Medchemexpress LLC HY-10261A 200mg , Afatinib (dimaleate) BIBW 2992MA2;BIBW2992;Afatinib CAS:850140-73-7 Purity:98%
Supplier: Medchemexpress LLC HY10261A200MG
Medchemexpress, HY-10261A 200mg Afatinib (dimaleate) BIBW 2992MA2;BIBW2992;Afatinib CAS:850140-73-7 Formula:C32H33ClFN5O11 IC50: 0.5 nM (EGFR wt ), 0.4 nM (EGFR L858R ), 10 nM (EGFR L858R/T790M ), 14 nM (HER2) Purity:98% Afatinib dimaleate is an irreversible, dual EGFR / HER2 inhibitor, shows potent activity against wild-type and mutant forms of EGFR and HER2, with IC 50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFR wt , EGFR L858R , EGFR L858R/T790M and HER2, respectively. Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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