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Medchemexpress LLC AG-636 | 1623416-31-8 | 98.07% | 343.38 | 1 ML
Supplier: Medchemexpress LLC HY13746310MM/1ML
AG-636 is a potent, reversible, selective, and orally active dihydroorotate dehydrogenase (DHODH) inhibitor. With an IC50 of 17 nM, it demonstrates strong anticancer effects and growth-inhibitory activity in various cancer cell lines. It has also shown robust tumor growth inhibition in xenograft lymphoma models.
- Potent, reversible, selective, and orally active DHODH inhibitor
- IC50 of 17 nM against DHODH
- Strong growth-inhibitory activity in cancer cell lines of hematologic versus solid tumor origin
- Robust tumor growth inhibition in xenograft lymphoma models
- Currently in phase 1 clinical trial for lymphoma
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