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Medchemexpress LLC ω-Agatoxin IVA TFA | 99.1% | 5316.27 | 5 MG
SDP

Supplier:  Medchemexpress LLC HYP1080A5MG

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ω-Agatoxin IVA TFA is a potent and selective blocker of P/Q type Ca2+ (Cav2.1) channels. It exhibits IC50s of 2 nM for P-type and 90 nM for Q-type Ca2+ channels. The compound inhibits glutamate exocytosis and calcium influx, as well as the release of serotonin and norepinephrine, when elicited by high potassium. It does not affect L-type or N-type calcium channels.

  • Potent and selective P/Q type Ca2+ (Cav2.1) channel blocker.
  • IC50s of 2 nM for P-type and 90 nM for Q-type Ca2+ channels.
  • Inhibits glutamate exocytosis and calcium influx.
  • Blocks high potassium-induced release of serotonin and norepinephrine.
  • Has no effect on L-type or N-type calcium channels.

Catalog No. 50-004-22997


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