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Medchemexpress LLC Agi-24512 | 2201066-53-5 | 99.5% | 400.47 | 1 ML
Supplier: Medchemexpress LLC HY11213010MM/1ML
AGI-24512 is a potent methionine adenosyltransferase 2α (MAT2A) inhibitor with an IC50 of 8 nM. It triggers DNA damage response and can block the proliferation of MTAP-deleted cancer cells in vitro. AGI-24512 can be used for researching anticancer properties.
- Triggers DNA damage response
- Blocks proliferation of MTAP-deleted cancer cells in vitro
- Inhibits PRMT5-mediated SDMA marks
- Leads to a dose-dependent decrease in SAM levels
- Suitable for anticancer research
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