Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
Learn More
Medchemexpress LLC AGI-5198 (IDH-C35) | 1355326-35-0 | 99.9% | 462.56 | 1 G
Supplier: Medchemexpress LLC HY180821G
AGI-5198 (IDH-C35) is a potent and selective mutant IDH1R132H inhibitor, with an IC50 of 0.07 μM. It is for research use only and demonstrates dose-dependent inhibition of the mutant IDH1 enzyme in TS603 glioma cells. AGI-5198 can also reverse the effects of increased reactive oxygen species, DNA double-strand breaks, and cell death in IDH1(R132H) mutated cancer cells after exposure to ionizing radiation. In vivo studies show it causes 50 to 60% growth inhibition of human glioma xenografts.
- Solid appearance with a white to off-white color
- Inhibits IDH1R132H mutant with an IC50 of 0.07 μM
- Soluble in DMF and DMSO for in vitro applications
- Available in powder and solvent forms for varied storage conditions
- Demonstrates significant growth inhibition in human glioma xenografts
Product Title
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.
Spot an opportunity for improvement?