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Cayman Chemical AH 10639phosphate 5mg

Supplier: Cayman Chemical 410435 MG

A PAR2 antagonist (IC50 72.4 nM in HT-29 cells expressing the human receptor) inhibits trypsin-induced calcium release in HT-29 cells (IC50 200 nM for the human receptor) reduces the migration of HT-29 cells in a scratch assay at 0.1 1 and 10 UM decreases 2f-LIGRL-NH2-induced expression of mRNA encoding CXCL8 in and secreted IL-8 levels from HT-29 cells at 1 and 10 UM inhibits tissue factor-induced clotting ex vivo using isolated human whole blood at 10 UM
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