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Enzo Life Sciences alpha-Hydroxyfarnesylphosphonic acid (1mg). CAS: 140633-12-1
Supplier: Enzo Life Sciences BMLG2280001
Potent inhibitor of farnesyltransferase in isolated enzyme assays (IC50=30 nM) and in whole cells. Inhibition of farnesyltransferase is selective over geranylgeranyltransferase I and II (IC50=35.8 µM and 67 µM respectively). α-Hydroxyfarnesylphosphonic acid inhibited (1 µM) Ras processing in Ha-ras-transformed NIH 3T3 fibroblasts. Formulation: Solution in ethanol. Purity: ≥98% (TLC). Long Term Storage: -20°C.
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