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AdipoGen AIM2 human mAb 3B10
Supplier: AdipoGen AG20B0040C100
Monoclonal Antibody. Recognizes human AIM2. Isotype Mouse IgG1. Clone 3B10. Applications ICC, WB. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. AIM2 is a strong candidate as a tumor suppressor as it is a member of the HIN-200 hemopoietic interferon-inducible, nuclear proteins containing a 200 amino acid repeat family of proteins that have been shown to regulate cell growth and survival. The HIN-200 family of proteins consists of four members in human, IFI 16, MNDA, AIM2 and IFIXl. Recently it has been reported that AIM2 is a receptor for cytosolic dsDNA, which forms a novel inflammasome complex with ASC to activate caspase-1-mediated processing of IL-1beta.
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