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Medchemexpress LLC AIMP2-DX2 inhibitor | 2421117-98-6 | 99.8% | 546.66 | 1 ML
SDP

Catalog No. 5000349494
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BC-DXI-843 is a potent and selective inhibitor that targets AIMP2-DX2, demonstrating an IC50 of 0.92 μM in a luciferase assay. This compound exhibits over 100-fold selectivity against AIMP2, making it a promising candidate for anti-cancer therapy, particularly in lung cancer. It effectively suppresses cancer cell proliferation in a DX2-dependent manner and shows efficacy in in vivo tumor models without significant changes in body weight, indicating its potential for specific therapeutic applications.

  • Potent and selective inhibition of AIMP2-DX2.
  • High selectivity over AIMP2.
  • Potential as a lead compound for lung cancer therapy.
  • Suppresses cancer cell proliferation in a DX2-dependent manner.
  • Demonstrates in vivo efficacy in tumor xenograft models.

Catalog No. 50-003-49494 Supplier Medchemexpress LLC Supplier No. HY13643110MM/1ML
May include imposed supplier surcharges.
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BC-DXI-843 is a potent and selective inhibitor that targets AIMP2-DX2, demonstrating an IC50 of 0.92 μM in a luciferase assay. This compound exhibits over 100-fold selectivity against AIMP2, making it a promising candidate for anti-cancer therapy, particularly in lung cancer. It effectively suppresses cancer cell proliferation in a DX2-dependent manner and shows efficacy in in vivo tumor models without significant changes in body weight, indicating its potential for specific therapeutic applications.

  • Potent and selective inhibition of AIMP2-DX2.
  • High selectivity over AIMP2.
  • Potential as a lead compound for lung cancer therapy.
  • Suppresses cancer cell proliferation in a DX2-dependent manner.
  • Demonstrates in vivo efficacy in tumor xenograft models.

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