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Medchemexpress LLC AITRL/TNFSF18 Mouse 50ug
SDP

Supplier:  Medchemexpress LLC HYP731950UG

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AITRL a type II transmembrane protein is a ligand for glucocorticoid-induced TNFR-related protein (GITR) When AITRL binds to GITR GITR can produce costimulatory signals that regulate T-cell proliferation and effector functions GITR/AITRL interaction plays a role in the pathogenesis of tumor inflammation as well as autoimmune diseases[1] Besides AITRL plays a role in endothelial cells (EC)-activation and increases STAT-1 phosphorylation and the expression of adhesion molecules (VCAM-1 ICAM-1)[2] AITRL/TNFSF18 Protein Mouse is a recombinant mouse AITRL (T47-S173) without tag which is expressed in E coli

Catalog No. 50-001-81159


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