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Medchemexpress LLC AITRL/TNFSF18 Trimer 50ug | 50ug
SDP

Supplier:  Medchemexpress LLC HYP7813350UG

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AITRL a type II transmembrane protein is a ligand for glucocorticoid-induced TNFR-related protein (GITR) When AITRL binds to GITR GITR can produce costimulatory signals that regulate T-cell proliferation and effector functions GITR/AITRL interaction plays a role in the pathogenesis of tumor inflammation as well as autoimmune diseases[1] Besides AITRL plays a role in endothelial cells (EC)-activation and increases STAT-1 phosphorylation and the expression of adhesion molecules (VCAM-1 ICAM-1)[2] AITRL/TNFSF18 Protein Human (Biotinylated HEK293 His-Flag) is a recombinant biotinylated human AITRL (Q72-S199) with N-terminal His and Flag tag which is expressed in HEK293

Catalog No. 50-001-93783


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