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Medchemexpress LLC Ak-778-xxmu | 1227045-76-2 | 100.0% | C22H17ClN2O3 | 10MG
SDP

Supplier:  Medchemexpress LLC HY14470710MG

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AK-778-XXMU is a small-molecule antagonist of DNA binding inhibitor 2 (ID2) used for research applications. It binds ID2 with a reported KD of 129 nM, inhibits glioma cell migration and invasion, induces apoptosis, and modulates ID2-KDR signaling to affect VEGFA, MMP2/9, and PTEN.

  • Potent ID2 binding (KD 129 nM).
  • Demonstrated inhibition of glioma cell migration and invasion.
  • Induces apoptosis in glioma cell lines.
  • Modulates angiogenesis and invasion-related signaling pathways.
  • High chemical purity (99.96%).
  • Soluble in DMSO at 100 mg/mL; ultrasonic may be required.
  • Stable as a powder at -20°C for long-term storage.

Catalog No. 50-002-58351


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