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Selleck Chemical LLC AKOS B018304
Supplier: Selleck Chemical LLC S68015MG
AKOS B018304 (C6 NSC 43396) is an arylalkylidene derivative with a polar substitution at the para-position It functions as an inhibitor of FosB by allosterically inhibiting its binding to DNA It disrupts FosB binding to TMR-cdk5 with an IC50 value of 10 1 M and also induces a structural change in FosB that prevents the protein from binding to DNA
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