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Echelon Biosciences Research LabsSupplier Diversity Partner AKT INHIBITOR (FPA-124) 5 mg  DFS Item

Manufacturer:  Echelon Biosciences Research LabsSupplier Diversity Partner B01015MG

FPA-124 is a cell-permeable inhibitor of Akt (IC50 = 100 nM), binding to the PH and kinase domains. It inhibits cell proliferation in Colo357, BxPC3, BT20, and PC3 cancer cell lines with IC50 values ranging from 7-55 nM. FPA-124 inhibited tumor growth in mice with negligible toxicity.\n\n


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Solubility

\nDMSO: 5 mg/mL\n

Storage

\nStore dry between 2-8oC. Stock solutions should be stored frozen (-20oC).\n

References

\n1) V. Barve, et al. "Synthesis, Molecular Characterization, and Biological Activity of Novel Synthetic


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