Invitrogen™ Human AKT2 (PKB beta), His Tag Recombinant Protein

Catalog No.	Quantity
PV3184	10 μg

Catalog No. PV3184 Supplier Invitrogen™ Supplier No. PV3184

Description

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Full Length.

AKT2 is a phosphoinositide-dependent serine/threonine protein kinase that is enriched in insulin responsive tissues and has been implicated in the metabolic actions of the hormone. Akt is involved in many cellular signaling pathways and acts as a transducer of many functions initiated by growth factor receptors that activate phosphatidylinositol 3-kinase (PI 3-kinase). Akt2 is amplified and overexpressed in some human cancers.

Specifications

• Accession Number: P31751
• Concentration: See Label
• For Use With (Application): Kinase Assay
• Formulation: 20mM tris with 0.01% Triton X-100, 20% glycerol, 2mM DTT, 150mM NaCl, 0.5mM EDTA, 0.1mM sodium orthovanadate and no preservative; pH 7.5
• Gene ID (Entrez): 208
• Molecular Weight (g/mol): 59.1 kDa
• Name: Human AKT2 (PKB beta), His Tag
• pH Range: 7.5
• Purification Method: Purified
• Quantity: 10 μg
• Storage Requirements: -80°C, Avoid Freeze/Thaw Cycles
• Regulatory Status: RUO
• Gene Alias: 2410016A19Rik; AKT serine/threonine kinase 2; Akt2; AKT2 kinase; AW554154; HIHGHH; murine thymoma viral (v-akt) homolog-2; murine thymoma viral (v-akt) oncogene homolog 2; PKB; PKB beta; PKBB; PKBBETA; PRKBB; protein kinase Akt-2; Protein kinase B beta; protein kinase B, beta; putative v-akt murine thymoma viral oncoprotein 2; rac protein kinase beta; RAC protein kinase beta RAC-PK beta; RAC-BETA; RAC-beta serine/threonine protein kinase; RAC-beta serine/threonine-protein kinase; RAC-PK-beta; thymoma viral proto-oncogene 2; v-akt murine thymoma viral oncogene homolog 2
• Common Name: AKT2
• Gene Symbol: Akt2
• Kinase Family: AKT Kinase Family
• Product Type: Protein
• Conjugate: Unconjugated
• Species: Human
• Recombinant: Recombinant
• Protein Tag: His-tag
• Sequence: Full length
• Content And Storage: Storage Buffer: 20mM Tris, pH 7.5, 150mM NaCl, 0.5mM EDTA, 0.01% Triton X-100, 0.1mM Na3VO4, 2mM DTT, 20% glycerol
  Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.
• Assay Entry: Biochemical terbium phospho-specific activity, Biochemical phospho-specific activity (no antibody)
• Kinase Group: Ser⁄Thr Kinases: ACG Group
• Shipping Condition: Dry Ice
• System Compatibility: LanthaScreen™ Antibody, LanthaScreen™ Substrate, Zin-LYTE™, Omnia™ Bulk Substrate
• Target Entry: AKT2
• Target Gene: v-akt murine thymoma viral oncogene homolog 2
• Expression System: Insect cells
• Protein Family: Kinases & Inhibitors
• Protein Form: Recombinant, Full Length
• Form: Liquid
• Protein Subtype: Serine/Threonine Kinases
• Research Category: Signal Transduction
• Purity or Quality Grade: 90% by SDS-PAGE