Alamethicin

Description

A channel-forming ionophore that activates membrane enzymes | CAS: 59588-86-2 | C92H150N22O25 | 1964.341 g/mol

Alamethicin is used as a channel-forming ionophore that activates membrane enzymes, membrane channel-forming peptide. It is a 20-amino acid channel-forming peptide antibiotic that can function as a monovalent cation ionophore. Alamethicin has been used to develop methods for the routine assessment of potential new drug candidates to elicit their pharmacokinetic drug interactions.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Alamethicin is used as a channel-forming ionophore that activates membrane enzymes, membrane channel-forming peptide. It is a 20-amino acid channel-forming peptide antibiotic that can function as a monovalent cation ionophore. Alamethicin has been used to develop methods for the routine assessment of potential new drug candidates to elicit their pharmacokinetic drug interactions.

Solubility
Soluble in DMSO and ethanol.

Notes
Protect from heat. Store away from oxidizing agents.

Specifications

Chemical Identifiers

• CAS: 59588-86-2
• Molecular Formula: C92H150N22O25
• Molecular Weight (g/mol): 1964.341
• MDL Number: MFCD00151517
• InChI Key: LGHSQOCGTJHDIL-SLKIUSOBSA-N
• Synonym: U-22324
• PubChem CID: 53229968
• SMILES: CC(C)CC(C(=O)NC(C)(C)C(=O)N1CCCC1C(=O)NC(C(C)C)C(=O)NC(C)(C)C(=O)NC(C)(C)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)N)C(=O)NC(CC2=CC=CC=C2)CO)NC(=O)CNC(=O)C(C)(C)NC(=O)C(C(C)C)NC(=O)C(C)(C)NC(=O)C(CCC(=O)N)NC(=O)C(C)NC(=O)C(C)(C)NC(=O)C(C)NC(=O)C(C)(C)NC(=O)C3CCCN3C

• Type: Alamethicin
• Physical Form: Powder
• Melting Point: 267°C to 270°C
• Color: White
• Quantity: 1 mg
• UN Number: UN3462
• Solubility Information: Soluble in DMSO and ethanol.
• Formula Weight: 1964.4
• Chemical Name or Material: Alamethicin

Safety and Handling

Hazard Category	H301
Hazard Statement	GHS H Statement H301 Toxic if swallowed.
Precautionary Statement	P264b-P270-P301+P310-P330-P501c
DOTInformation	Transport Hazard Class: 6.1; Packaging Group: III; Proper Shipping Name: TOXINS, EXTRACTED FROM LIVING SOURCES, SOLID, N.O.S.
RTECSNumber	AY1900000
TSCA	No
storageNote1	2° to 8°C
Recommended Storage	Keep cold

SDS

RUO – Research Use Only