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Alamethicin

Catalog No. AAJ63829MCR
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Description

A channel-forming ionophore that activates membrane enzymes | CAS: 59588-86-2 | C92H150N22O25 | 1964.341 g/mol

Alamethicin is used as a channel-forming ionophore that activates membrane enzymes, membrane channel-forming peptide. It is a 20-amino acid channel-forming peptide antibiotic that can function as a monovalent cation ionophore. Alamethicin has been used to develop methods for the routine assessment of potential new drug candidates to elicit their pharmacokinetic drug interactions.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Alamethicin is used as a channel-forming ionophore that activates membrane enzymes, membrane channel-forming peptide. It is a 20-amino acid channel-forming peptide antibiotic that can function as a monovalent cation ionophore. Alamethicin has been used to develop methods for the routine assessment of potential new drug candidates to elicit their pharmacokinetic drug interactions.

Solubility
Soluble in DMSO and ethanol.

Notes
Protect from heat. Store away from oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 59588-86-2
Molecular Formula C92H150N22O25
Molecular Weight (g/mol) 1964.341
MDL Number MFCD00151517
InChI Key LGHSQOCGTJHDIL-SLKIUSOBSA-N
Synonym U-22324
PubChem CID 53229968
SMILES CC(C)CC(C(=O)NC(C)(C)C(=O)N1CCCC1C(=O)NC(C(C)C)C(=O)NC(C)(C)C(=O)NC(C)(C)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)N)C(=O)NC(CC2=CC=CC=C2)CO)NC(=O)CNC(=O)C(C)(C)NC(=O)C(C(C)C)NC(=O)C(C)(C)NC(=O)C(CCC(=O)N)NC(=O)C(C)NC(=O)C(C)(C)NC(=O)C(C)NC(=O)C(C)(C)NC(=O)C3CCCN3C

Specifications

Type Alamethicin
Physical Form Powder
Melting Point 267°C to 270°C
Color White
Quantity 1 mg
UN Number UN3462
Solubility Information Soluble in DMSO and ethanol.
Formula Weight 1964.4
Chemical Name or Material Alamethicin

Safety and Handling

Hazard Category H301
Hazard Statement GHS H Statement
H301
Toxic if swallowed.
Precautionary Statement P264b-P270-P301+P310-P330-P501c
DOTInformation Transport Hazard Class: 6.1; Packaging Group: III; Proper Shipping Name: TOXINS, EXTRACTED FROM LIVING SOURCES, SOLID, N.O.S.
RTECSNumber AY1900000
TSCA No
storageNote1 2° to 8°C
Recommended Storage Keep cold
SDS

RUO – Research Use Only

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