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Avanti Polar Lipids ALC-0159, Methoxypolyethylene glycol conjugated lipid, 25 mg powder, Cationic Lipid, PEG-2000
Supplier: Avanti Polar Lipids 880155P25MG
ALC-0159 is a PEGylated lipid designed to enhance lipid nanoparticle (LNP) drug delivery systems, significantly improving the bioavailability of therapeutics. By forming a hydrophilic shield, it reduces immune recognition and extends systemic circulation. This excipient is crucial for mRNA-based vaccines, enabling efficient encapsulation and intracellular delivery, with applications in gene therapy and advanced pharmaceutical uses such as CRISPR and siRNA delivery.
- Cationic lipid and polymerizable lipid
- Empirical formula: C121H243NO47
- Molecular weight: 2464.20 Da
- Purity: >99%
- Form: Powder
- PEG moiety: PEG-2000
- Application: mRNA-based vaccines, nucleic acid delivery, gene therapy
- Storage temperature: -20°C
- Shipping: Dry ice
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