ALC-0159 is a PEGylated lipid designed to enhance the stability and biocompatibility of lipid nanoparticle (LNP) drug delivery systems. It significantly improves circulation time and bioavailability for therapeutics by reducing immune recognition, making it a key component in mRNA-based vaccines and other drug delivery applications.
- Enhanced stability and biocompatibility for LNP drug delivery
- Facilitates effective nanoparticle encapsulation and intracellular delivery
- Reduces immune recognition and improves bioavailability
- Essential for mRNA-based vaccines, including COVID-19 formulations
- Applicable in nucleic acid delivery, CRISPR, siRNA, and antisense oligonucleotides
- Soluble in ethanol, DMSO, and specific solvent combinations
- Stored at -20°C and shipped on dry ice
- High purity of over 99% (TLC)