Alcian Blue 8GX, MP Biomedicals™

Description

Shows ring structure with amidinothiomethyl groups. Alcian Blue 8GX, MP Biomedicals is a cationic dye used to quantitatively determine glycosaminoglycans by forming insoluble complexes in solution. The dye increases in selectivity when increasing amounts

Alcian Blue 8GX increases in selectivity when increasing amounts of magnesium chloride are added. In contrast, studies show that when electrolyte concentration is very low, it has trouble binding to carboxylate or phosphate groups.

• Quantitatively determine glycosaminoglycans by forming insoluble complexes in solution
• Determine proteins based on their Resonance Light Scattering by strongly enhancing the signals
• Useful as a bacterial stain and as a dye for histiocytes and fibroblasts
• Used as a heteroglycan stain for neutral, sulfated and phosphated mucopolysaccharides and glycosaminoglycans in tissues such as cartilage and extracellular matrices

Specifications

Chemical Identifiers

• CAS: 75881-23-1
• Molecular Formula: C56H68Cl4CuN16S4
• Molecular Weight (g/mol): 1298.858
• InChI Key: CKLBXIYTBHXJEH-UHFFFAOYSA-J
• Synonym: Alcian Blue, Ingrain Blue 1
• PubChem CID: 16211091
• SMILES: CN(C)C(=[N+](C)C)SCC1=CC2=C(C=C1)C3=NC4=NC(=NC5=C6C=C(C=CC6=C([N-]5)N=C7C8=C(C=CC(=C8)CSC(=[N+](C)C)N(C)C)C(=N7)N=C2[N-]3)CSC(=[N+](C)C)N(C)C)C9=C4C=C(C=C9)CSC(=[N+](C)C)N(C)C.[Cl-].[Cl-].[Cl-].[Cl-].[Cu+2]

• Solubility Information: Soluble in absolute ethanol, cellosolve, ethylene glycol, water (8mg/mL) or ethanol (1mg/mL); practically insoluble in xylene
• Formula Weight: 1298.88
• Quantity: 25 g
• Physical Form: Powder

Safety and Handling

Recommended Storage

Room Temperature

WARNING: Reproductive Harm - www.P65Warnings.ca.gov