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Medchemexpress LLC Aldehyde-benzyl-PEG5-alkyne | 1378928-83-6 | 97.09% | 336.38 | 100 MG
Supplier: Medchemexpress LLC HY136140100MG
Aldehyde-benzyl-PEG5-alkyne is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules possessing Azide groups. PROTACs themselves consist of two distinct ligands connected by a linker: one ligand targets an E3 ubiquitin ligase, and the other targets a specific protein, leveraging the intracellular ubiquitin-proteasome system for selective protein degradation. This product is intended for research use only.
- PEG-based PROTAC linker
- Click chemistry reagent
- Contains an alkyne group for CuAAc reactions
- Utilizes the ubiquitin-proteasome system for selective protein degradation
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