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Medchemexpress LLC Alectinib Hydrochloride | 1256589-74-8 | 99.9% | 200 MG
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Supplier:  Medchemexpress LLC HY13011A200MG

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Alectinib (CH5424802; RO5424802; RG7853) Hydrochloride is a potent, selective, and orally available ALK inhibitor. It has an IC50 of 1.9 nM and a Kd value of 2.4 nM (in an ATP-competitive manner). It also inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively. Alectinib demonstrates effective central nervous system (CNS) penetration.

  • Potent and selective ALK inhibitor
  • Orally available
  • Effective central nervous system (CNS) penetration
  • Inhibits ALK F1174L and ALK R1275Q

Catalog No. 50-003-38586


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